Repositorio Institucional Universidad EAFIT ::Examinando por Materia "Medical applications"

Examinando por Materia "Medical applications"

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Analysis of chemical processes for the synthesis of magnetite for biomedical applications
(IOP PUBLISHING LTD, 2011-01-01) Baena, J.; Marulanda, J.I.; Universidad EAFIT. Departamento de Ciencias Básicas; Óptica Aplicada
This article demonstrates the evaluation of wet chemical routes to produce magnetic nanoparticles of iron oxide and surface chemistry characterization by infrared spectroscopy (IR). Its potential use in biomedicine as contrast agents or to deliver drugs in localized medical treatments, which reduce the toxicity associated with cytotoxic drugs, is also evaluated.
Analysis of chemical processes for the synthesis of magnetite for biomedical applications
(IOP PUBLISHING LTD, 2011-01-01) Baena, J.; Marulanda, J.I.; Baena, J.; Marulanda, J.I.; Universidad EAFIT. Departamento de Ciencias; Electromagnetismo Aplicado (Gema)
This article demonstrates the evaluation of wet chemical routes to produce magnetic nanoparticles of iron oxide and surface chemistry characterization by infrared spectroscopy (IR). Its potential use in biomedicine as contrast agents or to deliver drugs in localized medical treatments, which reduce the toxicity associated with cytotoxic drugs, is also evaluated.
A comparative computational study of blood flow pattern in exemplary textile vascular grafts
(Taylor and Francis Ltd., 2018-01-01) Valencia, R.A.; García, M.J.; Bustamante, J.; Mecánica Aplicada
Textile vascular grafts are biomedical devices and play an important role serving as a solution for the partial replacement of damaged arterial vessels. It is believed that the success of a textile vascular graft, in the healing process after implantation, is due to the porous micro-structure of the wall. Although the transport of fluids through textiles is of great technical interest in biomedical applications, little is known about predicting the micro-flow pattern and cellular transport through the wall. The aim of this work is to investigate how the type of fabric, permeability and porosity affect both the local fluid dynamics at several scales and the fluid-particle interaction between platelets in textile grafts, related with the graft occlusion. This study involves both experimental and computational tests. Experimental tests are performed to characterize the permeability and porosity according to the ISO 7198 standard. The numerical process is based on a multi-scale approach where the fluid flow is solved with the Finite Element Method and the discrete particles are solved with the Molecular Dynamic Method. The results have shown that the type of fabric in textile vascular grafts and the degree of porosity and permeability affect both the local fluid dynamics and the level of penetration of platelets through the wall, thus indicating their importance as design parameters. © 2017 Informa UK Limited, trading as Taylor & Francis Group.
A comparative computational study of blood flow pattern in exemplary textile vascular grafts
(Taylor and Francis Ltd., 2018-01-01) R. VALENCIA; M. GARCÍA; J. BUSTAMANTE; R. VALENCIA; M. GARCÍA; J. BUSTAMANTE; Universidad EAFIT. Departamento de Humanidades; Centro de Estudios Urbanos y Ambientales (URBAM)
Textile vascular grafts are biomedical devices and play an important role serving as a solution for the partial replacement of damaged arterial vessels. It is believed that the success of a textile vascular graft, in the healing process after implantation, is due to the porous micro-structure of the wall. Although the transport of fluids through textiles is of great technical interest in biomedical applications, little is known about predicting the micro-flow pattern and cellular transport through the wall. The aim of this work is to investigate how the type of fabric, permeability and porosity affect both the local fluid dynamics at several scales and the fluid-particle interaction between platelets in textile grafts, related with the graft occlusion. This study involves both experimental and computational tests. Experimental tests are performed to characterize the permeability and porosity according to the ISO 7198 standard. The numerical process is based on a multi-scale approach where the fluid flow is solved with the Finite Element Method and the discrete particles are solved with the Molecular Dynamic Method. The results have shown that the type of fabric in textile vascular grafts and the degree of porosity and permeability affect both the local fluid dynamics and the level of penetration of platelets through the wall, thus indicating their importance as design parameters. © 2017 Informa UK Limited, trading as Taylor & Francis Group.
Comparison of TiO2 targets manufactured by APS and sintering processes for PAPVD coatings suitable in technological and medical applications
(ASM International, 2018-01-01) Jaramillo Raquejo D.; Palacio C.C.; Ageorges H.; Jaramillo Raquejo D.; Palacio C.C.; Ageorges H.; Universidad EAFIT. Departamento de Ciencias; Electromagnetismo Aplicado (Gema)
In surface science of functional oxides, Titanium dioxide (TiO2) is one of the most investigated crystalline systems either in rutile or anatase phases. Rutile phase is widely used in microelectronic, tribological applications and in the conversion of solar energy. Anatase phase is used in self-cleaning, antifogging, photo-catalytic and biomedical technologies. This work focuses on studying the required process conditions to obtain TiO2 targets by APS onto metallic substrates using commercial TiO2 powders (Oerlikon Metco in Switzerland) with suitable physical and chemical properties for technological and medical applications as PAPVD coatings. APS targets were compared to sintered ones. The raw powders were characterized by laser diffraction, SEM, XRF and XRD while the characteristics of the APS-deposited targets as well as the sintered ones were determined by SEM and XRD to identify the constituent phases. This work allowed confirming the advantages and limitations of both processes in terms of grain size, chemical composition, microstructural homogeneity and density in order to choose the best option to manufacture targets for PAPVD coatings for technological and medical applications. © 2018 ASM International® All rights reserved.
mantisGRID: a grid platform for DICOM medical images management in Colombia and Latin America.
(SPRINGER, 2011-04-01) Garcia Ruiz M; García, A.; Ruiz Ibañez C; Gutierrez Mazo JM; Ramirez Giraldo JC; Pelaez Echavarria A; Valencia Diaz E; Pelaez Restrepo G; Montoya Munera EN; Garcia Loaiza B; Gomez Gonzalez S; Garcia Ruiz M; García, A.; Ruiz Ibañez C; Gutierrez Mazo JM; Ramirez Giraldo JC; Pelaez Echavarria A; Valencia Diaz E; Pelaez Restrepo G; Montoya Munera EN; Garcia Loaiza B; Gomez Gonzalez S; Universidad EAFIT. Departamento de Ingeniería de Sistemas; I+D+I en Tecnologías de la Información y las Comunicaciones
This paper presents the mantisGRID project, an interinstitutional initiative from Colombian medical and academic centers aiming to provide medical grid services for Colombia and Latin America. The mantisGRID is a GRID platform, based on open source grid infrastructure that provides the necessary services to access and exchange medical images and associated information following digital imaging and communications in medicine (DICOM) and health level 7 standards. The paper focuses first on the data abstraction architecture, which is achieved via Open Grid Services Architecture Data Access and Integration (OGSA-DAI) services and supported by the Globus Toolkit. The grid currently uses a 30-Mb bandwidth of the Colombian High Technology Academic Network, RENATA, connected to Internet 2. It also includes a discussion on the relational database created to handle the DICOM objects that were represented using Extensible Markup Language Schema documents, as well as other features implemented such as data security, user authentication, and patient confidentiality. Grid performance was tested using the three current operative nodes and the results demonstrated comparable query times between the mantisGRID (OGSA-DAI) and Distributed mySQL databases, especially for a large number of records.
mantisGRID: a grid platform for DICOM medical images management in Colombia and Latin America.
(SPRINGER, 2011-04-01) Garcia Ruiz M; García, A.; Ruiz Ibañez C; Gutierrez Mazo JM; Ramirez Giraldo JC; Pelaez Echavarria A; Valencia Diaz E; Pelaez Restrepo G; Montoya Munera EN; Garcia Loaiza B; Gomez Gonzalez S; Universidad EAFIT. Departamento de Ingeniería Mecánica; Bioingeniería GIB (CES – EAFIT)
This paper presents the mantisGRID project, an interinstitutional initiative from Colombian medical and academic centers aiming to provide medical grid services for Colombia and Latin America. The mantisGRID is a GRID platform, based on open source grid infrastructure that provides the necessary services to access and exchange medical images and associated information following digital imaging and communications in medicine (DICOM) and health level 7 standards. The paper focuses first on the data abstraction architecture, which is achieved via Open Grid Services Architecture Data Access and Integration (OGSA-DAI) services and supported by the Globus Toolkit. The grid currently uses a 30-Mb bandwidth of the Colombian High Technology Academic Network, RENATA, connected to Internet 2. It also includes a discussion on the relational database created to handle the DICOM objects that were represented using Extensible Markup Language Schema documents, as well as other features implemented such as data security, user authentication, and patient confidentiality. Grid performance was tested using the three current operative nodes and the results demonstrated comparable query times between the mantisGRID (OGSA-DAI) and Distributed mySQL databases, especially for a large number of records.
Robotic research platform for image-guided surgery assistance
(2013-01-01) Cortes, C.A.; Barandiaran, I.; Ruiz, O.E.; De Mauro, A.; Universidad EAFIT. Departamento de Ingeniería Mecánica; Laboratorio CAD/CAM/CAE
In the context of surgery, it is very common to face challenging scenarios during the preoperative plan implementation. The surgical technique's complexity, the human anatomical variability and the occurrence of unexpected situations generate issues for the intervention's goals achievement. To support the surgeon, robotic systems are being integrated to the operating room. However, current commercial solutions are specialized for a particular technique or medical application, being difficult to integrate with other systems. Thus, versatile and modular systems are needed to conduct several procedures and to help solving the problems that surgeons face. This article aims to describe the implementation of a robotic research platform prototype that allows novel applications in the field of image-guided surgery. In particular, this research is focused on the topics of medical image acquisition during surgery, patient registration and surgical/medical equipment operation. In this paper, we address the implementation of the general purpose teleoperation and path following modes of the platform, which constitute the base of future developments. Also, we discuss relevant aspects of the system, as well as future directions and application fields to investigate.
Study of APS and conventional sintering parameters for the manufacture of TiO2 targets for PAPVD
(IOP PUBLISHING LTD, 2019-01-01) Jaramillo Raquejo D.; Palacio C.C.; Ageorges H.; Jaramillo Raquejo D.; Palacio C.C.; Ageorges H.; Universidad EAFIT. Departamento de Ciencias; Electromagnetismo Aplicado (Gema)
In surface science of functional oxides, titanium dioxide (TiO2) is one of the most investigated crystalline systems either in rutile or anatase phases. In this work commercial TiO2 powders are used to study the required process conditions to obtain TiO2 targets by Atmospheric Plasma Spray (APS) and conventional sintering, with suitable physical and chemical properties to be source material for Plasma Assisted Physical Vapor Deposition (PAPVD) for technological and medical applications. Two three factor Box Behnken experimental designs combined with surface modeling were employed to estimate the influence of spraying parameters (gun current, Ar/H2 ratio and standoff distance) and sintering parameters (heating rate, sintering temperature and holding time) within the targets microstructure (cracks and pores in cross section) and phases composition. The microstructure and composition of APS-deposited targets and sintered ones were characterized by Scanning Electron Microscopy (SEM) and X-Ray Diffraction (XRD). The lowest defects percentages of the targets manufactured in this work were 0.41 ± 0.30 % for APS-deposited targets and 0.05 ± 0.04 % for the sintered ones using the optimal parameters suggested by the statistical model, which allowed confirming the advantages of sintering process and limitations of APS in terms of microstructural homogeneity, but also of the use of design of experiments in the modeling of systems of many variables when there is not diagnostic equipment of the processes available. © Published under licence by IOP Publishing Ltd.
Study of the suitability of a commercial hydroxyapatite powder to obtain sintered compacts for medical applications
(IOP PUBLISHING LTD, 2017-06-13) Palacio C.; Jaramillo D.; Correa S.; Arroyave M.; Palacio C.; Jaramillo D.; Correa S.; Arroyave M.; Universidad EAFIT. Departamento de Ciencias; Electromagnetismo Aplicado (Gema)
Hydroxyapatite (HA) is a material widely used by the medical community due to its Ca/P ratio is comparable to the Ca/P ratio of bones and teeth, which promotes osteoinduction and osteoconduction processes when in contact with bone tissue, either as volume piece or coating. This work focuses on studying the quality of the commercial HA powder MKnano-#MKN-HXAP-S12 µm, after processing, to obtain sintered compact discs with suitable physical and chemical characteristics for implants applications. The HA powder was processed through calcination, grinding, pressing and sintering to evaluate the effect of such as procedures in the compacts dics quality. The raw powder was characterized by laser diffraction, SEM, XRF, XRD, TGA and DSC while the characteristics of the obtained compact discs were determined by dilatometry and XRD to identify the sintering temperature range, constituent phases, the amorphous content and the crystallinity degree, parameters that allow determining their suitability for implants applications. Although, it was not possible to obtain sintered compacts with the suitable chemical composition and without fractures, this work allowed to identify the parameters that determine the suitability of a HA powder to obtain sintered compacts for medical applications, as well as the characterization protocol that allows the evaluation of such parameters. © Published under licence by IOP Publishing Ltd.
Study of the suitability of a commercial hydroxyapatite powder to obtain sintered compacts for medical applications
(IOP PUBLISHING LTD, 2017-06-13) Palacio C.; Jaramillo D.; Correa S.; Arroyave M.
Hydroxyapatite (HA) is a material widely used by the medical community due to its Ca/P ratio is comparable to the Ca/P ratio of bones and teeth, which promotes osteoinduction and osteoconduction processes when in contact with bone tissue, either as volume piece or coating. This work focuses on studying the quality of the commercial HA powder MKnano-#MKN-HXAP-S12 µm, after processing, to obtain sintered compact discs with suitable physical and chemical characteristics for implants applications. The HA powder was processed through calcination, grinding, pressing and sintering to evaluate the effect of such as procedures in the compacts dics quality. The raw powder was characterized by laser diffraction, SEM, XRF, XRD, TGA and DSC while the characteristics of the obtained compact discs were determined by dilatometry and XRD to identify the sintering temperature range, constituent phases, the amorphous content and the crystallinity degree, parameters that allow determining their suitability for implants applications. Although, it was not possible to obtain sintered compacts with the suitable chemical composition and without fractures, this work allowed to identify the parameters that determine the suitability of a HA powder to obtain sintered compacts for medical applications, as well as the characterization protocol that allows the evaluation of such parameters. © Published under licence by IOP Publishing Ltd.
Study of the suitability of a commercial hydroxyapatite powder to obtain sintered compacts for medical applications
(IOP PUBLISHING LTD, 2017-06-13) Palacio C.; Jaramillo D.; Correa S.; Arroyave M.; Universidad EAFIT. Departamento de Ingeniería Mecánica; Bioingeniería GIB (CES – EAFIT)
Hydroxyapatite (HA) is a material widely used by the medical community due to its Ca/P ratio is comparable to the Ca/P ratio of bones and teeth, which promotes osteoinduction and osteoconduction processes when in contact with bone tissue, either as volume piece or coating. This work focuses on studying the quality of the commercial HA powder MKnano-#MKN-HXAP-S12 µm, after processing, to obtain sintered compact discs with suitable physical and chemical characteristics for implants applications. The HA powder was processed through calcination, grinding, pressing and sintering to evaluate the effect of such as procedures in the compacts dics quality. The raw powder was characterized by laser diffraction, SEM, XRF, XRD, TGA and DSC while the characteristics of the obtained compact discs were determined by dilatometry and XRD to identify the sintering temperature range, constituent phases, the amorphous content and the crystallinity degree, parameters that allow determining their suitability for implants applications. Although, it was not possible to obtain sintered compacts with the suitable chemical composition and without fractures, this work allowed to identify the parameters that determine the suitability of a HA powder to obtain sintered compacts for medical applications, as well as the characterization protocol that allows the evaluation of such parameters. © Published under licence by IOP Publishing Ltd.

Examinando por Materia "Medical applications"

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