(R)-alpha-Lipoic acid treatment restores ceramide balance in aging rat cardiac mitochondria

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dc.citation.journalTitlePHARMACOL RESspa
dc.contributor.authorMonette, Jeffrey S.
dc.contributor.authorGómez, Luis A.
dc.contributor.authorMoreau, Regis
dc.contributor.authorDunn, Kevin C.
dc.contributor.authorButler, Judy A.
dc.contributor.authorFinlay, Liam A.
dc.contributor.authorMichels, Alexander J.
dc.contributor.authorPetersen-Shay, Kate
dc.contributor.authorSmith, Eric J.
dc.contributor.authorHagen, Tory M.
dc.contributor.departmentUniversidad EAFIT. Departamento de Cienciasspa
dc.contributor.researchgroupCiencias Biológicas y Bioprocesos (CIBIOP)spa
dc.date.accessioned2021-03-23T20:08:58Z
dc.date.available2021-03-23T20:08:58Z
dc.date.issued2011-01-01
dc.description.abstractInflammation results in heightened mitochondrial ceramide levels, which cause electron transport chain dysfunction, elevates reactive oxygen species, and increases apoptosis. As mitochondria in aged hearts also display many of these characteristics, we hyeng
dc.identifierhttps://eafit.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=5031
dc.identifier.doi10.1016/j.phrs.2010.09.007spa
dc.identifier.issn10436618spa
dc.identifier.issn10961186spa
dc.identifier.urihttp://hdl.handle.net/10784/26813
dc.language.isoengeng
dc.publisherElsevier Inc.
dc.relation.urihttps://www.ncbi.nlm.nih.gov/pubmed/20934512
dc.rightshttps://v2.sherpa.ac.uk/id/publication/issn/1043-6618
dc.sourcePHARMACOL RES
dc.subject.keywordAgingeng
dc.subject.keywordSphingomyelinaseeng
dc.subject.keywordLC-mass spectrometryeng
dc.subject.keywordElectron transporteng
dc.subject.keywordComplex IVeng
dc.title(R)-alpha-Lipoic acid treatment restores ceramide balance in aging rat cardiac mitochondriaeng
dc.typearticleeng
dc.typeinfo:eu-repo/semantics/articleeng
dc.typeinfo:eu-repo/semantics/publishedVersioneng
dc.typepublishedVersioneng
dc.type.localArtículo

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