Understanding the extraction capabilities of the Helix Supercritical Fluid System
Fecha
2018
Autores
Guzmán Aristizábal, Paola Andrea
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Editor
Universidad EAFIT
Resumen
Supercritical fluids extraction is a separation technique, which has higher yields and lower extraction times than conventional extraction techniques -- Moreover, due to the general use of carbon dioxide a supercritical medium there is also a reduction in the use of toxic organic solvents -- Although there are commercial supercritical fluid extraction systems, these systems are not standardized, and each different system has its own particularities -- At Universidad EAFIT there is a new supercritical fluid equipment, a Helix model of Applied Separations, that has not been thoroughly tested for its operation -- The extraction of glycosides from stevia was used as a model for understanding the effect of different parameters, such as pressure, temperature, CO2 flow, matrix load and extraction time, on the operation the Helix system at EAFIT University -- The effect of the changes in the variables was evaluated by calculating extraction yield and by characterization of the extract -- The obtained extract was characterized by IR and HPLC to verify the extraction of glycosides -- As a result of this project an operation manual for the equipment was written -- Pressure seems to be the more influential operating parameter, both for the matrix extraction and equipment performance -- Pressure and temperature have repercussions on other process variables as preparing, extraction and cleaning time or 𝐶𝑂2 consumption -- However, all the evaluated operating parameters represent a contribution for the equipment performance and their understanding is essential for improved capability of Helix system -- A maximum yield of 1.4% was obtained -- Pressure was the most important variable on the glycosides extraction yield, while the temperature did not have a noticeable effect on the yield -- Similarly, the use of cosolvent remarkably improved the performance at same conditions of pressure and temperature -- An approximate extraction time of 120 minutes was required