Repositorio Institucional Universidad EAFIT ::Examinando por Materia "Bone"

Examinando por Materia "Bone"

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Biomechanics of the canine mandible during bone transport distraction osteogenesis
(ASME, 2014-11-01) Zapata, Uriel; Dechow, Paul C.; Watanabe, Ikuya; Elsalanty, Mohammed E.; Opperman, Lynne A.; Universidad EAFIT. Departamento de Ingeniería Mecánica; Bioingeniería GIB (CES – EAFIT)
This study compared biomechanical patterns between finite element models (FEMs) and a fresh dog mandible tested under molar and incisal physiological loads in order to clarify the effect of the bone transport distraction osteogenesis (BTDO) surgical process. Three FEMs of dog mandibles were built in order to evaluate the effects of BTDO. The first model evaluated the mandibular response under two physiological loads resembling bite processes. In the second model, a 5.0 cm bone defect was bridged with a bone transport reconstruction plate (BTRP). In the third model, new regenerated bony tissue was incorporated within the defect to mimic the surgical process without the presence of the device. Complementarily, a mandible of a male American foxhound dog was mechanically tested in the laboratory both in the presence and absence of a BTRP, and mechanical responses were measured by attaching rosettes to the bone surface of the mandible to validate the FEM predictions. The relationship between real and predicted values indicates that the stress patterns calculated using FEM are a valid predictor of the biomechanics of the BTDO procedures. The present study provides an interesting correlation between the stiffness of the device and the biomechanical response of the mandible affected for bone transport. Copyright © 2014 by ASME.
Biomechanics of the canine mandible during bone transport distraction osteogenesis
(ASME, 2014-11-01) Zapata, Uriel; Dechow, Paul C.; Watanabe, Ikuya; Elsalanty, Mohammed E.; Opperman, Lynne A.; Zapata, Uriel; Dechow, Paul C.; Watanabe, Ikuya; Elsalanty, Mohammed E.; Opperman, Lynne A.; Universidad EAFIT. Departamento de Ingeniería de Producción; Materiales de Ingeniería
This study compared biomechanical patterns between finite element models (FEMs) and a fresh dog mandible tested under molar and incisal physiological loads in order to clarify the effect of the bone transport distraction osteogenesis (BTDO) surgical process. Three FEMs of dog mandibles were built in order to evaluate the effects of BTDO. The first model evaluated the mandibular response under two physiological loads resembling bite processes. In the second model, a 5.0 cm bone defect was bridged with a bone transport reconstruction plate (BTRP). In the third model, new regenerated bony tissue was incorporated within the defect to mimic the surgical process without the presence of the device. Complementarily, a mandible of a male American foxhound dog was mechanically tested in the laboratory both in the presence and absence of a BTRP, and mechanical responses were measured by attaching rosettes to the bone surface of the mandible to validate the FEM predictions. The relationship between real and predicted values indicates that the stress patterns calculated using FEM are a valid predictor of the biomechanics of the BTDO procedures. The present study provides an interesting correlation between the stiffness of the device and the biomechanical response of the mandible affected for bone transport. Copyright © 2014 by ASME.
Design and manufacture of custom cranial implants
(SPRINGER, 2013-01-01) J. ISAZA; S. CORREA; J. FRANCO; C. TORRES; B. BEDOYA; Universidad EAFIT. Departamento de Humanidades; Estudios de Filosofía, Hermenéutica y Narrativas
Problem statement: Cranioplasty is defined as a neurosurgical procedure to cover an injured bone in the skull. This procedure is carried out in order to protect and restore intracranial structures and to restore the appearance and psychological stability
In vitro mechanical evaluation of mandibular bone transport devices
(ASME, 2014-06-01) Zapata, Uriel; Watanabe, Ikuya; Opperman, Lynne A.; Dechow, Paul C.; Mulone, Timothy; Elsalanty, Mohammed E.; Zapata, Uriel; Watanabe, Ikuya; Opperman, Lynne A.; Dechow, Paul C.; Mulone, Timothy; Elsalanty, Mohammed E.; Universidad EAFIT. Departamento de Ingeniería de Producción; Materiales de Ingeniería
Bone transport distraction osteogenesis (BTDO) is a surgical procedure that has been used over the last 30 years for the correction of segmental defects produced mainly by trauma and oncological resections. Application of BTDO has several clinical advantages over traditional surgical techniques. Over the past few years, several BTDO devices have been introduced to reconstruct mandibular bone defects. Based on the location and outline of the defect, each device requires a uniquely shaped reconstruction plate. To date, no biomechanical evaluations of mandibular BTDO devices have been reported in the literature. The present study evaluated the mechanical behavior of three different shaped prototypes of a novel mandibular bone transport reconstruction plate and its transport unit for the reconstruction of segmental bone defects of the mandible by using numerical models complemented with mechanical laboratory tests to characterize strength, fatigue, and stability. The strength test evaluated device failures under extreme loads and was complemented with optimization procedures to improve the biomechanical behavior of the devices. The responses of the prototypes were characterized to improve their design and identify weak and strong regions in order to avoid posterior device failure in clinical applications. Combinations of the numerical and mechanical laboratory results were used to compare and validate the models. In addition, the results remark the importance of reducing the number of animals used in experimental tests by increasing computational and in vitro trials. © VC 2014 by ASME.
In vitro mechanical evaluation of mandibular bone transport devices
(ASME, 2014-06-01) Zapata, Uriel; Watanabe, Ikuya; Opperman, Lynne A.; Dechow, Paul C.; Mulone, Timothy; Elsalanty, Mohammed E.; Universidad EAFIT. Departamento de Ingeniería Mecánica; Bioingeniería GIB (CES – EAFIT)
Bone transport distraction osteogenesis (BTDO) is a surgical procedure that has been used over the last 30 years for the correction of segmental defects produced mainly by trauma and oncological resections. Application of BTDO has several clinical advantages over traditional surgical techniques. Over the past few years, several BTDO devices have been introduced to reconstruct mandibular bone defects. Based on the location and outline of the defect, each device requires a uniquely shaped reconstruction plate. To date, no biomechanical evaluations of mandibular BTDO devices have been reported in the literature. The present study evaluated the mechanical behavior of three different shaped prototypes of a novel mandibular bone transport reconstruction plate and its transport unit for the reconstruction of segmental bone defects of the mandible by using numerical models complemented with mechanical laboratory tests to characterize strength, fatigue, and stability. The strength test evaluated device failures under extreme loads and was complemented with optimization procedures to improve the biomechanical behavior of the devices. The responses of the prototypes were characterized to improve their design and identify weak and strong regions in order to avoid posterior device failure in clinical applications. Combinations of the numerical and mechanical laboratory results were used to compare and validate the models. In addition, the results remark the importance of reducing the number of animals used in experimental tests by increasing computational and in vitro trials. © VC 2014 by ASME.
Meta-modeling of Lattice Mechanical Responses via Design of Experiments
(Institute of Electrical and Electronics Engineers Inc., 2020-01-01) Montoya-Zapata D.; Acosta D.A.; Cortes C.; Pareja-Corcho J.; Moreno A.; Posada J.; Ruiz-Salguero O.; Universidad EAFIT. Departamento de Ingeniería de Procesos; Desarrollo y Diseño de Procesos
In the context of lattice manufacturing, the problem of mechanical and structural characterization of large lattice domains is relevant. Lattice materials are used in engineering (e.g. in energy absorption and heat conduction) and biomedical (e.g. bone implants and artificial tissues) applications. However, the numerical simulation of large lattice domains is limited by its complicated geometry, which hinders the meshing stage and produces intractable finite element meshes. The existing efforts to simulate large lattice domains are based on the generation of simplified homogeneous domains equipped with material properties that approximate the behavior of the lattice domain equipped with the bulk material. Using this approach, one can estimate the displacements field over the lattice domain using a lighter mesh and a cheaper simulation. However, since stresses are influenced by geometrical conditions, the stresses of the simplified domain do not match the stresses of the lattice domain. As a response to this limitation, this article proposes a methodology based on the systematic use of design of experiments to devise meta-models to estimate the mechanical response of lattice domains. The devised meta-models can be integrated with material homogenization to allow the mechanical characterization of large lattice domains. In this paper, we apply the proposed methodology to develop meta-models for the estimation of the von Mises stress in Schwarz Primitive lattice domains. Results show that the proposed methodology is able to generate efficient and accurate meta-models whose inputs are based on the displacements on the boundary of the Schwarz cell. Therefore, numerical simulations with the homogeneous simplified domain can be used to feed the meta-models. Additional work is still required to integrate the developed meta-models with material homogenization to test large Schwarz Primitive lattice domains under working loads. © 2020 IEEE.
Meta-modeling of Lattice Mechanical Responses via Design of Experiments
(Institute of Electrical and Electronics Engineers Inc., 2020-01-01) Montoya-Zapata D.; Acosta D.A.; Cortes C.; Pareja-Corcho J.; Moreno A.; Posada J.; Ruiz-Salguero O.; Montoya-Zapata D.; Acosta D.A.; Cortes C.; Pareja-Corcho J.; Moreno A.; Posada J.; Ruiz-Salguero O.; Universidad EAFIT. Departamento de Ingeniería de Procesos; Procesos Ambientales (GIPAB)
In the context of lattice manufacturing, the problem of mechanical and structural characterization of large lattice domains is relevant. Lattice materials are used in engineering (e.g. in energy absorption and heat conduction) and biomedical (e.g. bone implants and artificial tissues) applications. However, the numerical simulation of large lattice domains is limited by its complicated geometry, which hinders the meshing stage and produces intractable finite element meshes. The existing efforts to simulate large lattice domains are based on the generation of simplified homogeneous domains equipped with material properties that approximate the behavior of the lattice domain equipped with the bulk material. Using this approach, one can estimate the displacements field over the lattice domain using a lighter mesh and a cheaper simulation. However, since stresses are influenced by geometrical conditions, the stresses of the simplified domain do not match the stresses of the lattice domain. As a response to this limitation, this article proposes a methodology based on the systematic use of design of experiments to devise meta-models to estimate the mechanical response of lattice domains. The devised meta-models can be integrated with material homogenization to allow the mechanical characterization of large lattice domains. In this paper, we apply the proposed methodology to develop meta-models for the estimation of the von Mises stress in Schwarz Primitive lattice domains. Results show that the proposed methodology is able to generate efficient and accurate meta-models whose inputs are based on the displacements on the boundary of the Schwarz cell. Therefore, numerical simulations with the homogeneous simplified domain can be used to feed the meta-models. Additional work is still required to integrate the developed meta-models with material homogenization to test large Schwarz Primitive lattice domains under working loads. © 2020 IEEE.
Meta-modeling of Lattice Mechanical Responses via Design of Experiments
(Institute of Electrical and Electronics Engineers Inc., 2020-01-01) Montoya-Zapata D.; Acosta D.A.; Cortes C.; Pareja-Corcho J.; Moreno A.; Posada J.; Ruiz-Salguero O.; Universidad EAFIT. Departamento de Ingeniería Mecánica; Laboratorio CAD/CAM/CAE
In the context of lattice manufacturing, the problem of mechanical and structural characterization of large lattice domains is relevant. Lattice materials are used in engineering (e.g. in energy absorption and heat conduction) and biomedical (e.g. bone implants and artificial tissues) applications. However, the numerical simulation of large lattice domains is limited by its complicated geometry, which hinders the meshing stage and produces intractable finite element meshes. The existing efforts to simulate large lattice domains are based on the generation of simplified homogeneous domains equipped with material properties that approximate the behavior of the lattice domain equipped with the bulk material. Using this approach, one can estimate the displacements field over the lattice domain using a lighter mesh and a cheaper simulation. However, since stresses are influenced by geometrical conditions, the stresses of the simplified domain do not match the stresses of the lattice domain. As a response to this limitation, this article proposes a methodology based on the systematic use of design of experiments to devise meta-models to estimate the mechanical response of lattice domains. The devised meta-models can be integrated with material homogenization to allow the mechanical characterization of large lattice domains. In this paper, we apply the proposed methodology to develop meta-models for the estimation of the von Mises stress in Schwarz Primitive lattice domains. Results show that the proposed methodology is able to generate efficient and accurate meta-models whose inputs are based on the displacements on the boundary of the Schwarz cell. Therefore, numerical simulations with the homogeneous simplified domain can be used to feed the meta-models. Additional work is still required to integrate the developed meta-models with material homogenization to test large Schwarz Primitive lattice domains under working loads. © 2020 IEEE.
Study of the suitability of a commercial hydroxyapatite powder to obtain sintered compacts for medical applications
(IOP PUBLISHING LTD, 2017-06-13) Palacio C.; Jaramillo D.; Correa S.; Arroyave M.; Palacio C.; Jaramillo D.; Correa S.; Arroyave M.; Universidad EAFIT. Departamento de Ciencias; Electromagnetismo Aplicado (Gema)
Hydroxyapatite (HA) is a material widely used by the medical community due to its Ca/P ratio is comparable to the Ca/P ratio of bones and teeth, which promotes osteoinduction and osteoconduction processes when in contact with bone tissue, either as volume piece or coating. This work focuses on studying the quality of the commercial HA powder MKnano-#MKN-HXAP-S12 µm, after processing, to obtain sintered compact discs with suitable physical and chemical characteristics for implants applications. The HA powder was processed through calcination, grinding, pressing and sintering to evaluate the effect of such as procedures in the compacts dics quality. The raw powder was characterized by laser diffraction, SEM, XRF, XRD, TGA and DSC while the characteristics of the obtained compact discs were determined by dilatometry and XRD to identify the sintering temperature range, constituent phases, the amorphous content and the crystallinity degree, parameters that allow determining their suitability for implants applications. Although, it was not possible to obtain sintered compacts with the suitable chemical composition and without fractures, this work allowed to identify the parameters that determine the suitability of a HA powder to obtain sintered compacts for medical applications, as well as the characterization protocol that allows the evaluation of such parameters. © Published under licence by IOP Publishing Ltd.
Study of the suitability of a commercial hydroxyapatite powder to obtain sintered compacts for medical applications
(IOP PUBLISHING LTD, 2017-06-13) Palacio C.; Jaramillo D.; Correa S.; Arroyave M.
Hydroxyapatite (HA) is a material widely used by the medical community due to its Ca/P ratio is comparable to the Ca/P ratio of bones and teeth, which promotes osteoinduction and osteoconduction processes when in contact with bone tissue, either as volume piece or coating. This work focuses on studying the quality of the commercial HA powder MKnano-#MKN-HXAP-S12 µm, after processing, to obtain sintered compact discs with suitable physical and chemical characteristics for implants applications. The HA powder was processed through calcination, grinding, pressing and sintering to evaluate the effect of such as procedures in the compacts dics quality. The raw powder was characterized by laser diffraction, SEM, XRF, XRD, TGA and DSC while the characteristics of the obtained compact discs were determined by dilatometry and XRD to identify the sintering temperature range, constituent phases, the amorphous content and the crystallinity degree, parameters that allow determining their suitability for implants applications. Although, it was not possible to obtain sintered compacts with the suitable chemical composition and without fractures, this work allowed to identify the parameters that determine the suitability of a HA powder to obtain sintered compacts for medical applications, as well as the characterization protocol that allows the evaluation of such parameters. © Published under licence by IOP Publishing Ltd.
Study of the suitability of a commercial hydroxyapatite powder to obtain sintered compacts for medical applications
(IOP PUBLISHING LTD, 2017-06-13) Palacio C.; Jaramillo D.; Correa S.; Arroyave M.; Universidad EAFIT. Departamento de Ingeniería Mecánica; Bioingeniería GIB (CES – EAFIT)
Hydroxyapatite (HA) is a material widely used by the medical community due to its Ca/P ratio is comparable to the Ca/P ratio of bones and teeth, which promotes osteoinduction and osteoconduction processes when in contact with bone tissue, either as volume piece or coating. This work focuses on studying the quality of the commercial HA powder MKnano-#MKN-HXAP-S12 µm, after processing, to obtain sintered compact discs with suitable physical and chemical characteristics for implants applications. The HA powder was processed through calcination, grinding, pressing and sintering to evaluate the effect of such as procedures in the compacts dics quality. The raw powder was characterized by laser diffraction, SEM, XRF, XRD, TGA and DSC while the characteristics of the obtained compact discs were determined by dilatometry and XRD to identify the sintering temperature range, constituent phases, the amorphous content and the crystallinity degree, parameters that allow determining their suitability for implants applications. Although, it was not possible to obtain sintered compacts with the suitable chemical composition and without fractures, this work allowed to identify the parameters that determine the suitability of a HA powder to obtain sintered compacts for medical applications, as well as the characterization protocol that allows the evaluation of such parameters. © Published under licence by IOP Publishing Ltd.

Examinando por Materia "Bone"

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