Supercomplexes of the mitochondrial electron transport chain decline in the aging rat heart

Fecha

2009-10-01

Autores

Gómez, Luis A.
Monette, Jeffrey S.
Chavez, Juan D.
Maier, Claudia S.
Hagen, Tory M.

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ELSEVIER SCIENCE INC

Resumen

Accumulation of mitochondrial electron transport chain (ETC) defects is a recognized hallmark of the age-associated decline in cardiac bioenergetics; however, the molecular events involved are only poorly understood. In the present work,

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