Cost-effectiveness analysis of thermotherapy versus pentavalent antimonials for the treatment of cutaneous leishmaniasis

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dc.contributor.authorCardona-Arias, Jaiberth Antonio
dc.contributor.authorLópez Carvajal, Liliana
dc.contributor.authorTamayo Plata, Mery Patricia
dc.contributor.authorVeléz, Iván Darío
dc.contributor.eafitauthorjaiberthcardona@gmail.co
dc.contributor.eafitauthorlililopez14@gmail.com
dc.contributor.eafitauthormptamayo@eafit.edu.co
dc.contributor.eafitauthoridvelez@pecet-colombia.org
dc.coverage.spatialMedellín de: Lat: 06 15 00 N degrees minutes Lat: 6.2500 decimal degrees Long: 075 36 00 W degrees minutes Long: -75.6000 decimal degreeseng
dc.date.accessioned2018-06-26T13:45:52Z
dc.date.available2018-06-26T13:45:52Z
dc.date.issued2018-02-01
dc.description.abstractIntroduction: The treatment of cutaneous leishmaniasis is toxic, has contraindications and a high cost. Objective: To estimate the cost-effectiveness of thermotherapy versus pentavalent antimonials for the treatment of cutaneous leishmaniasis. Methods: Effectiveness was the proportion of healing, and safety with the adverse effects; these parameters were estimated from a controlled clinical trial and a meta-analysis. A standard costing were conducted. Average and incremental cost-effectiveness ratios were estimated. The uncertainty regarding effectiveness, safety and costs was determined through sensitivity analyses. Results: The total costs were $66,807 with Glucantime and $14,079 with thermotherapy. The therapeutic effectiveness rates were 64.2% for thermotherapy and 85.1% for Glucantime. The average cost-effectiveness ratios ranged between $721 and $1,275 for Glucantime and between $187 and $390 for thermotherapy. Based on the meta-analysis thermotherapy may be a dominant strategy. Conclusion: The excellent cost-effectiveness ratio of thermotherapy shows the relevance of its inclusion in guidelines for the treatment.eng
dc.identifier.urihttp://hdl.handle.net/10784/12419
dc.language.isoengeng
dc.publisherUniversidad EAFITspa
dc.publisher.departmentEscuela de Economía y Finanzasspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccesseng
dc.rights.localAcceso abiertospa
dc.subject.keywordCost-effectiveness analysiseng
dc.subject.keywordAnálisis costo-efectivospa
dc.subject.keywordCutaneous leishmaniasiseng
dc.subject.keywordLeishmaniasis cutáneaspa
dc.subject.keywordThermotherapyeng
dc.subject.keywordTermoterapiaspa
dc.subject.keywordGluconato de antimonio sódicospa
dc.subject.keywordColombiaspa
dc.titleCost-effectiveness analysis of thermotherapy versus pentavalent antimonials for the treatment of cutaneous leishmaniasiseng
dc.typeworkingPapereng
dc.typeinfo:eu-repo/semantics/workingPapereng
dc.type.hasVersiondrafteng
dc.type.localDocumento de trabajo de investigaciónspa

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