Fengycin C produced by Bacillus subtilis EA-CB0015

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dc.citation.epage509spa
dc.citation.issue4spa
dc.citation.journalAbbreviatedTitleJNPspa
dc.citation.journalTitleJournal of the Natural Productsspa
dc.citation.spage503spa
dc.citation.volume76spa
dc.contributor.authorCeballos, Isabel
dc.contributor.authorJ. Mira, John
dc.contributor.authorArgel, Luz Edith
dc.contributor.authorOrduz Peralta, Sergio
dc.contributor.authorRomero Tabarez, Magally
dc.contributor.authorVillegas Escobar, Valeska
dc.contributor.departmentCentro de Investigaciones del Banano
dc.contributor.departmentInstituto de Biotecnología, Universidad Nacional de Colombia, Bogotá
dc.contributor.departmentUniversidad Nacional de Colombia, Medellín
dc.contributor.departmentUniversidad EAFIT. Departamento de Cienciasspa
dc.contributor.eafitauthorValeska Villegas Escobar ( vvilleg2@eafit.edu.co.)spa
dc.contributor.researchgroupCiencias Biológicas y Bioprocesos (CIBIOP)spa
dc.date.accessioned2015-08-13T14:22:22Z
dc.date.available2015-08-13T14:22:22Z
dc.date.issued2014
dc.description.abstractBacillus subtilis EA-CB0015 was isolated from the phyllosphere of a banana plant and tested for its potential to produce bioactive compounds against Mycosphaerella fijiensis -- Using a dual plate culture technique the cell-free supernatant of B. subtilis EA-CB0015 produced inhibition values of 89 ± 1% -- The active compounds were purified by solid-phase extraction and HPLC, and their primary structures determined using mass spectrometry and amino acid analysis -- A new fengycin isoform, fengycin C, with the amino acid sequence Glu-Orn-Tyr-Thr-Glu-Val-Pro-Gln-Thr-Ile was isolated -- The peptidic moiety differs from fengycin B at position 9 and from fengycin A at positions 6 and 9 -- The β-hydroxy fatty acyl chain is connected to the N-terminal of the decapeptide and can be saturated or unsaturated, ranging from 14 to 18 carbons -- The C-terminal residue of the peptidic moiety is linked to the tyrosine residue at position 3, forming the branching point of the acyl peptide and the eight-membered cyclic lactoneeng
dc.identifier.doi10.1021/np300574vspa
dc.identifier.issn0163-3864spa
dc.identifier.otherWOS;000371949100002
dc.identifier.otherPUBMED;26802972
dc.identifier.otherSCOPUS;2-s2.0-84958777738
dc.identifier.urihttp://hdl.handle.net/10784/7258
dc.language.isoengeng
dc.publisherAmerican Chemical Societyspa
dc.relation.ispartofJournal of the Natural Products (JNP), Volume 76 , Issue 4, pp 503-509spa
dc.relation.urihttp://pubs.acs.org/doi/abs/10.1021/np300574v
dc.rightsCopyright © 2013 The American Chemical Society and American Society of Pharmacognosyspa
dc.rights.accessrightsinfo:eu-repo/semantics/restrictedAccessspa
dc.rights.localAcceso restringidospa
dc.subject.keywordBacillus subtiliseng
dc.subject.keywordBioactive compoundseng
dc.subject.keywordMass spectrometryeng
dc.subject.keywordAmino acidseng
dc.subject.keywordPhytopathogenic fungieng
dc.subject.keywordOrganic cyclic compoundseng
dc.subject.keywordLactoneseng
dc.subject.keywordTirosinaspa
dc.subject.keywordFengycinspa
dc.subject.lembBACILLUS SUBTILISspa
dc.subject.lembCOMPUESTOS BIOACTIVOSspa
dc.subject.lembESPECTROMETRÍA DE MASASspa
dc.subject.lembAMINOÁCIDOSspa
dc.subject.lembHONGOS FITOPATÓGENOSspa
dc.subject.lembCOMPUESTOS ORGANOCÍCLICOSspa
dc.subject.lembLACTONASspa
dc.titleFengycin C produced by Bacillus subtilis EA-CB0015eng
dc.typearticleeng
dc.typeinfo:eu-repo/semantics/articleeng
dc.typeinfo:eu-repo/semantics/publishedVersioneng
dc.typepublishedVersioneng
dc.type.localArtículo

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