Artículos

URI permanente para esta colección

https://hdl.handle.net/10784/7942

Examinar

Examinando Artículos por Materia "article"

Mostrando 1 - 3 de 3
  • No hay miniatura disponible
    Publicación
    Deterministic SIR (Susceptible-Infected-Removed) models applied to varicella outbreaks.
    (CAMBRIDGE UNIV PRESS, 2008-05-01) Giraldo JO; Palacio DH; Universidad EAFIT. Departamento de Ciencias; Lógica y Computación
    Deterministic SIR models were applied to simulate Susceptible-Infected-Removed and to estimate the threshold condition for varicella outbreaks in children, reported in Medellin, Colombia. The expected numbers of susceptible, infected and removed individuals were compared with observed cases from notification of varicella outbreaks to the local Board of Health and from survey data. The threshold condition was estimated by the basic reproductive ratio and by the relative removal rate, through which measures for preventing and curtailing the outbreaks were identified. The model demonstrated a reasonable fit to the observations, except in two of the six outbreaks which probably reflected under-registration of cases. In order to have prevented these outbreaks, between 4.4% and 52.9% of the susceptible population should have been vaccinated assuming an 85% vaccine effectiveness. Similarly, isolation of affected children should have been increased to between 4.3% and 44.8% per week.
  • No hay miniatura disponible
    Ítem
    mantisGRID: a grid platform for DICOM medical images management in Colombia and Latin America.
    (SPRINGER, 2011-04-01) Garcia Ruiz M; García, A.; Ruiz Ibañez C; Gutierrez Mazo JM; Ramirez Giraldo JC; Pelaez Echavarria A; Valencia Diaz E; Pelaez Restrepo G; Montoya Munera EN; Garcia Loaiza B; Gomez Gonzalez S; Garcia Ruiz M; García, A.; Ruiz Ibañez C; Gutierrez Mazo JM; Ramirez Giraldo JC; Pelaez Echavarria A; Valencia Diaz E; Pelaez Restrepo G; Montoya Munera EN; Garcia Loaiza B; Gomez Gonzalez S; Universidad EAFIT. Departamento de Ingeniería de Sistemas; I+D+I en Tecnologías de la Información y las Comunicaciones
    This paper presents the mantisGRID project, an interinstitutional initiative from Colombian medical and academic centers aiming to provide medical grid services for Colombia and Latin America. The mantisGRID is a GRID platform, based on open source grid infrastructure that provides the necessary services to access and exchange medical images and associated information following digital imaging and communications in medicine (DICOM) and health level 7 standards. The paper focuses first on the data abstraction architecture, which is achieved via Open Grid Services Architecture Data Access and Integration (OGSA-DAI) services and supported by the Globus Toolkit. The grid currently uses a 30-Mb bandwidth of the Colombian High Technology Academic Network, RENATA, connected to Internet 2. It also includes a discussion on the relational database created to handle the DICOM objects that were represented using Extensible Markup Language Schema documents, as well as other features implemented such as data security, user authentication, and patient confidentiality. Grid performance was tested using the three current operative nodes and the results demonstrated comparable query times between the mantisGRID (OGSA-DAI) and Distributed mySQL databases, especially for a large number of records.
  • No hay miniatura disponible
    Publicación
    Two-dimensional transport analysis of transdermal drug absorption with a non-perfect sink boundary condition at the skin-capillary interface
    (ELSEVIER SCIENCE INC, 2013-07-01) Simon, Laurent; Ospina, Juan; Universidad EAFIT. Departamento de Ciencias; Lógica y Computación
    A transient percutaneous drug absorption model was solved in two dimensions. Clearance of the topically-applied pharmaceutical occured at the skin-capillary boundary. Timolol penetration profiles in the dermal tissue were produced revealing concentration gradients in the directions normal and parallel to the skin surface. Ninety-eight percent of the steady-state flux was reached after 85. h or four time constants. The analytical solution procedure agreed with published results. As the clearance rate increased relative to diffusion, the delivery rate and amount of drug absorbed into the bloodstream increased while the time to reach the equilibrium flux decreased. Researchers can apply the closed-form expressions to simulate the process, estimate key parameters and design devices that meet specific performance requirements. © 2013 Elsevier Inc.