2021-04-162016-01-010716875607180764SCOPUS;2-s2.0-84994662243http://hdl.handle.net/10784/29452In this work, parametric sensitivity and dynamic analysis were combined to determine the thermal instability conditions inherent in the methyl isocyanate hydrolysis reaction. This highly exothermic reaction tragically proved to be very sensible to temperature changes in the so-called Bhopal disaster in 1984. A stirred tank reactor in transient state was considered for simulating the reactive system. First, critical operational conditions were defined from the parametric sensitivity analysis. Subsequently, in a rigorous way, the dynamic analysis determined the thermal instability regions, Hopf bifurcations, and the thermal oscillatory behavior of the reactive system. The Matcont® software was used to solve the differential equations set. It was demonstrated that runaway conditions and the periodic solutions of temperature are closely related with the cooling temperature and the dimensionless parameters (f-dimensionless flow and l-heat transfer term) and their critical parameters were obtained: /c=752.39 and fc=1.57.spahttps://v2.sherpa.ac.uk/id/publication/issn/0716-8756info:eu-repo/semantics/conferencePaperDifferential equationsDynamic analysisHeat transferHopf bifurcationHydrolysisThermodynamic stabilityDimensionless parametersMethyl isocyanateOperational conditionsOscillatory behaviorsParametric sensitivityParametric sensitivity analysisStirred tank reactorsThermal instabilitiesSensitivity analysis2021-04-16Ojeda, J.C.GilPavas, E.Dobrosz-Gómez, I.Gómez, M.A.10.4067/S0718-07642016000500006