2021-03-232020-01-011548709115487105http://hdl.handle.net/10784/26847We present ReDU (https://redu.ucsd.edu/), a system for metadata capture of public mass spectrometry-based metabolomics data, with validated controlled vocabularies. Systematic capture of knowledge enables the reanalysis of public data and/or co-analysis of one’s own data. ReDU enables multiple types of analyses, including finding chemicals and associated metadata, comparing the shared and different chemicals between groups of samples, and metadata-filtered, repository-scale molecular networking. © 2020, The Author(s), under exclusive licence to Springer Nature America, Inc.engNature Publishing Grouparticlearticlecontrolled studycontrolled vocabularymass spectrometrymetabolomicsmetadata2021-03-23Jarmusch A.K.Wang M.Aceves C.M.Advani R.S.Aguirre S.Aksenov A.A.Aleti G.Aron A.T.Bauermeister A.Bolleddu S.Bouslimani A.Caraballo Rodriguez A.M.Chaar R.Coras R.Elijah E.O.Ernst M.Gauglitz J.M.Gentry E.C.Husband M.Jarmusch S.A.Jones K.L.IIKamenik Z.Le Gouellec A.Lu A.McCall L.-I.McPhail K.L.Meehan M.J.Melnik A.V.Menezes R.C.Montoya Giraldo Y.A.Nguyen N.H.Nothias L.F.Nothias-Esposito M.Panitchpakdi M.Petras D.Quinn R.A.Sikora N.van der Hooft J.J.J.Vargas F.Vrbanac A.Weldon K.C.Knight R.Bandeira N.Dorrestein P.C.10.1038/s41592-020-0916-7