2015-08-1320140163-3864WOS;000371949100002PUBMED;26802972SCOPUS;2-s2.0-84958777738http://hdl.handle.net/10784/7258Bacillus subtilis EA-CB0015 was isolated from the phyllosphere of a banana plant and tested for its potential to produce bioactive compounds against Mycosphaerella fijiensis -- Using a dual plate culture technique the cell-free supernatant of B. subtilis EA-CB0015 produced inhibition values of 89 ± 1% -- The active compounds were purified by solid-phase extraction and HPLC, and their primary structures determined using mass spectrometry and amino acid analysis -- A new fengycin isoform, fengycin C, with the amino acid sequence Glu-Orn-Tyr-Thr-Glu-Val-Pro-Gln-Thr-Ile was isolated -- The peptidic moiety differs from fengycin B at position 9 and from fengycin A at positions 6 and 9 -- The β-hydroxy fatty acyl chain is connected to the N-terminal of the decapeptide and can be saturated or unsaturated, ranging from 14 to 18 carbons -- The C-terminal residue of the peptidic moiety is linked to the tyrosine residue at position 3, forming the branching point of the acyl peptide and the eight-membered cyclic lactoneengCopyright © 2013 The American Chemical Society and American Society of Pharmacognosyarticleinfo:eu-repo/semantics/restrictedAccessBACILLUS SUBTILISCOMPUESTOS BIOACTIVOSESPECTROMETRÍA DE MASASAMINOÁCIDOSHONGOS FITOPATÓGENOSCOMPUESTOS ORGANOCÍCLICOSLACTONASBacillus subtilisBioactive compoundsMass spectrometryAmino acidsPhytopathogenic fungiOrganic cyclic compoundsLactonesTirosinaFengycinAcceso restringido2015-08-13Ceballos, IsabelJ. Mira, JohnArgel, Luz EdithOrduz Peralta, SergioRomero Tabarez, MagallyVillegas Escobar, Valeska10.1021/np300574v