2020-12-032017-01-010798-1015SCOPUS;2-s2.0-85028337482http://hdl.handle.net/10784/24521The commercialization of new knowledge represents a great challenge for higher education institutions (HEI) today. In this paper, we conducted a qualitative research using findings from interviews and observations in technology transfer offices (TTO) in seven HEI in Colombia, Spain and the United States. The results helped in identifying the key factors that influence the process of commercialization of new knowledge. At the same time, this paper proposes a roadmap to help universities, researchers and professionals in charge of TTOs with this process. © 2017. revistaESPACIOS.com. Derechos Reservados.spahttps://v2.sherpa.ac.uk/id/publication/issn/0798-1015info:eu-repo/semantics/articleCommercialization of new knowledgeHigher education institutionsKey factorsTechnology transfer2020-12-03Franco L.Gentilin M.