Three-dimensional evaluation of mandibular bone regenerated by bone transport distraction osteogenesis

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dc.citation.journalTitleCALCIFIED TISSUE INTERNATIONALeng
dc.contributor.authorKontogiorgos, E.
dc.contributor.authorElsalanty, M.E.
dc.contributor.authorZapata, U.
dc.contributor.authorZakhary, I.
dc.contributor.authorNagy, W.W.
dc.contributor.authorDechow, P.C.
dc.contributor.authorOpperman, L.A.
dc.contributor.departmentUniversidad EAFIT. Departamento de Ingeniería Mecánicaspa
dc.contributor.researchgroupBioingeniería GIB (CES – EAFIT)spa
dc.date.accessioned2021-04-12T18:59:07Z
dc.date.available2021-04-12T18:59:07Z
dc.date.issued2011-07-01
dc.description.abstractThe purpose of this study was to evaluate the structure and material properties of native mandibular bone and those of early regenerate bone, produced by bone transport distraction osteogenesis. Ten adult foxhounds were divided into two groups of five animals each. In all animals, a 3- to 4-cm defect was created on one side of the mandible. A bone transport reconstruction plate, consisting of a reconstruction plate with an attached intraoral transport unit, was utilized to stabilize the mandible and regenerate bone at a rate of 1 mm/day. After the distraction period was finished, the animals were killed at 6 and 12 weeks of consolidation. Micro-computed tomography was used to assess the morphometric and structural indices of regenerate bone and matching bone from the unoperated contralateral side. Significant new bone was formed within the defect in the 6- and 12-week groups. Significant differences (P = 0.05) between mandibular regenerated and native bone were found in regard to bone volume fraction, mineral density, bone surface ratio, trabecular thickness, trabecular separation, and connectivity density, which increased from 12 to 18 weeks of consolidation. We showed that regenerated bone is still mineralizing and that native bone appears denser because of a thick outer layer of cortical bone that is not yet formed in the regenerate. However, the regenerate showed a significantly higher number of thicker trabeculae. © 2011 Springer Science+Business Media, LLC.eng
dc.identifierhttps://eafit.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2098
dc.identifier.doi10.1007/s00223-011-9492-2
dc.identifier.issn0171967X
dc.identifier.issn14320827
dc.identifier.otherWOS;000291390300006
dc.identifier.otherPUBMED;21556698
dc.identifier.otherSCOPUS;2-s2.0-79959693223
dc.identifier.urihttp://hdl.handle.net/10784/28149
dc.language.isoeng
dc.publisherSPRINGER
dc.relationDOI;10.1007/s00223-011-9492-2
dc.relationWOS;000291390300006
dc.relationPUBMED;21556698
dc.relationSCOPUS;2-s2.0-79959693223
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-79959693223&doi=10.1007%2fs00223-011-9492-2&partnerID=40&md5=3e72d673b42ce1b26274ecd2d3a2784c
dc.rightshttps://v2.sherpa.ac.uk/id/publication/issn/0171-967X
dc.sourceCALCIFIED TISSUE INTERNATIONAL
dc.subjectanimal celleng
dc.subjectanimal experimenteng
dc.subjectanimal modeleng
dc.subjectarticleeng
dc.subjectbone densityeng
dc.subjectbone developmenteng
dc.subjectbone plateeng
dc.subjectbone regenerationeng
dc.subjectbone structureeng
dc.subjectbone tissueeng
dc.subjectcontrolled studyeng
dc.subjectcortical boneeng
dc.subjectdistraction osteogenesiseng
dc.subjectdogeng
dc.subjecthistopathologyeng
dc.subjectleg lengtheningeng
dc.subjectmandibleeng
dc.subjectmandible reconstructioneng
dc.subjectmicro-computed tomographyeng
dc.subjectmorphometricseng
dc.subjectnonhumaneng
dc.subjectossificationeng
dc.subjectpriority journaleng
dc.subjectthree dimensional imagingeng
dc.subjecttrabecular boneeng
dc.subjectAnimalseng
dc.subjectBone Densityeng
dc.subjectBone Regenerationeng
dc.subjectDogseng
dc.subjectMandibleeng
dc.subjectOsteogenesiseng
dc.subjectOsteogenesiseng
dc.subjectDistractioneng
dc.subjectX-Ray Microtomographyeng
dc.titleThree-dimensional evaluation of mandibular bone regenerated by bone transport distraction osteogenesiseng
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typeinfo:eu-repo/semantics/articleeng
dc.typearticleeng
dc.typeinfo:eu-repo/semantics/publishedVersioneng
dc.typepublishedVersioneng
dc.type.localArtículospa

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