Architecture and microstructure of cortical bone in reconstructed canine mandibles after bone transport distraction osteogenesis

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dc.citation.journalTitleCALCIFIED TISSUE INTERNATIONAL
dc.contributor.authorZapata, Uriel
dc.contributor.authorHalvachs, Emily K.
dc.contributor.authorDechow, Paul C.
dc.contributor.authorElsalanty, Mohammed E.
dc.contributor.authorOpperman, Lynne A.
dc.contributor.departmentUniversidad EAFIT. Departamento de Ingeniería de Producciónspa
dc.contributor.researchgroupMateriales de Ingenieríaspa
dc.creatorZapata, Uriel
dc.creatorHalvachs, Emily K.
dc.creatorDechow, Paul C.
dc.creatorElsalanty, Mohammed E.
dc.creatorOpperman, Lynne A.
dc.date.accessioned2021-04-12T21:26:42Z
dc.date.available2021-04-12T21:26:42Z
dc.date.issued2011-11-01
dc.description.abstractReconstruction of the canine mandible using bone transport distraction osteogenesis has been shown to be a suitable method for correcting segmental bone defects produced by cancer, gunshots, and trauma. Although the mechanical quality of the new regenerate cortical bone seems to be related to the mineralization process, several questions regarding the microstructural patterns of the new bony tissue remain unanswered. The purpose of this study was to quantify any microstructural differences that may exist between the regenerate and control cortical bone. Five adult American foxhound dogs underwent unilateral bone transport distraction of the mandible to repair bone defects of 30-35 mm. Animals were killed 12 weeks after the beginning of the consolidation period. Fourteen cylindrical cortical samples were extracted from the superior, medial, and inferior aspects of the lingual and buccal plates of the reconstructed aspect of the mandible, and 21 specimens were collected similarly from the contralateral aspect of the mandible. Specimens were evaluated using histomorphometric and micro-computed tomographic techniques to compare their microstructure. Except for differences in haversian canal area, histomorphometric analyses suggested no statistical differences in microstructure between regenerate and control cortical bone. Morphological evaluation suggested a consistent level of anisotropy, possibly related to the distraction vector. After 12 weeks' consolidation, bone created during bone transport distraction osteogenesis was comparable to native bone in microstructure, architecture, and mechanical properties. It is proposed that, after enough time, the properties of the regenerate bone will be identical to that of native bone. © Springer Science+Business Media, LLC 2010.eng
dc.identifierhttps://eafit.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=1580
dc.identifier.doi10.1007/s00223-011-9529-6
dc.identifier.issn0171967X
dc.identifier.issn14320827
dc.identifier.otherWOS;000295846100004
dc.identifier.otherPUBMED;21927873
dc.identifier.otherSCOPUS;2-s2.0-82755160749
dc.identifier.urihttp://hdl.handle.net/10784/29081
dc.language.isoeng
dc.publisherSPRINGER
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-82755160749&doi=10.1007%2fs00223-011-9529-6&partnerID=40&md5=4661ef94c248fafee0e4b9ddb4e4d3ce
dc.rightshttps://v2.sherpa.ac.uk/id/publication/issn/0171-967X
dc.sourceCALCIFIED TISSUE INTERNATIONAL
dc.subjectadult animaleng
dc.subjectanimal experimenteng
dc.subjectanimal tissueeng
dc.subjectanisotropyeng
dc.subjectarticleeng
dc.subjectbiomechanicseng
dc.subjectbone defecteng
dc.subjectbone microstructureeng
dc.subjectbone regenerationeng
dc.subjectbone structureeng
dc.subjectcontrolled studyeng
dc.subjectcortical boneeng
dc.subjectcraniofacial morphologyeng
dc.subjectdistraction osteogenesiseng
dc.subjectexternal fixatoreng
dc.subjectHaversian canaleng
dc.subjectmaleeng
dc.subjectmandible reconstructioneng
dc.subjectmicro-computed tomographyeng
dc.subjectmorphometricseng
dc.subjectnonhumaneng
dc.subjectpriority journaleng
dc.subjectAnimalseng
dc.subjectBone Regenerationeng
dc.subjectDogseng
dc.subjectInternal Fixatorseng
dc.subjectMandibleeng
dc.subjectOsteogenesiseng
dc.subjectDistractioneng
dc.titleArchitecture and microstructure of cortical bone in reconstructed canine mandibles after bone transport distraction osteogenesiseng
dc.typeinfo:eu-repo/semantics/articleeng
dc.typearticleeng
dc.typeinfo:eu-repo/semantics/publishedVersioneng
dc.typepublishedVersioneng
dc.type.localArtículospa

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