Examinando por Materia "evolution"

Mostrando 1 - 4 de 4
  • Miniatura
    Ítem
    Biology and Economics: Metaphors that Economists usually take from Biology
    (Universidad EAFIT, 21/10/2007) García Callejas, Danny; Universidad de Antioquia
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    Ítem
    Ceratocystis cacaofunesta genome analysis reveals a large expansion of extracellular phosphatidylinositol-specific phospholipase-C genes (PI-PLC)
    (BioMed Central Ltd., 2018-01-17) Molano, E.P.L.; Cabrera, O.G.; Jose, J.; do Nascimento, L.C.; Carazzolle, M.F.; Teixeira, P.J.P.L.; Alvarez, J.C.; Tiburcio, R.A.; Tokimatu Filho, P.M.; de Lima, G.M.A.; Guido, R.V.C.; Corrêa, T.L.R.; Leme, A.F.P.; Mieczkowski, P.; Pereira, G.A.G.; Universidad EAFIT. Departamento de Ciencias; Biodiversidad, Evolución y Conservación
    Background: The Ceratocystis genus harbors a large number of phytopathogenic fungi that cause xylem parenchyma degradation and vascular destruction on a broad range of economically important plants. Ceratocystis cacaofunesta is a necrotrophic fungus responsible for lethal wilt disease in cacao. The aim of this work is to analyze the genome of C. cacaofunesta through a comparative approach with genomes of other Sordariomycetes in order to better understand the molecular basis of pathogenicity in the Ceratocystis genus. Results: We present an analysis of the C. cacaofunesta genome focusing on secreted proteins that might constitute pathogenicity factors. Comparative genome analyses among five Ceratocystidaceae species and 23 other Sordariomycetes fungi showed a strong reduction in gene content of the Ceratocystis genus. However, some gene families displayed a remarkable expansion, in particular, the Phosphatidylinositol specific phospholipases-C (PI-PLC) family. Also, evolutionary rate calculations suggest that the evolution process of this family was guided by positive selection. Interestingly, among the 82 PI-PLCs genes identified in the C. cacaofunesta genome, 70 genes encoding extracellular PI-PLCs are grouped in eight small scaffolds surrounded by transposon fragments and scars that could be involved in the rapid evolution of the PI-PLC family. Experimental secretome using LC-MS/MS validated 24% (86 proteins) of the total predicted secretome (342 proteins), including four PI-PLCs and other important pathogenicity factors. Conclusion: Analysis of the Ceratocystis cacaofunesta genome provides evidence that PI-PLCs may play a role in pathogenicity. Subsequent functional studies will be aimed at evaluating this hypothesis. The observed genetic arsenals, together with the analysis of the PI-PLC family shown in this work, reveal significant differences in the Ceratocystis genome compared to the classical vascular fungi, Verticillium and Fusarium. Altogether, our analyses provide new insights into the evolution and the molecular basis of plant pathogenicity. © 2018 The Author(s).
  • Miniatura
    Ítem
    Organizational evolution: socio-biological basis for understanding the metaphor
    (Universidad EAFIT, 2015-06-02) Lara Rodríguez, Juan Sebastián; Rojas Contreras, Camilo Andrés; Martínez Buitrago, Jenyfeer Andrea; Cnpq; University of Campinas; Colciencias; National University of Colombia
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    Ítem
    The philosopher and scientist of the twenty-first century
    (UNIV COMPROMETIDOS EXCELENCIA, 2015-01-01) L. TORO PALACIO; Departamento de Humanidades; Estudios de Filosofía, Hermenéutica y Narrativas
    Thinking about the work of Max Weber, more specifically, in The Politician and the Scientific, this understanding and analysis exercise is carried out around the evolution of the routine of the Philosopher and the Scientific in contemporary life. The analysis is aimed to the supposed ``death of philosophy'', deducted by Stephen Hawking. It is shown the way as the philosophy, the science and the universe increase with the time its complexity, and the way its evolution is incorporated in a dimension increasingly wide of the reality. Reality that we appropriate according to our level of understanding, by two movements that are ``one'': ``knowledge of being'' (possible for life and presences) and ``know the world'' (scientifically valuable). Today, the Philosopher resounds with the first movement and the scientific with the second one. It is understood that the hypothetical evolution of consciousness is the combination of two movements: a humanist scientific knowledge of who we are as a species and as individuals.