Examinando por Materia "boundary condition"
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Ítem Modeling the sediment dynamics in the gulf of Urabá colombian Caribbean sea(Elsevier Ltd, 2018-01-01) Escobar C.A.; Velásquez-Montoya L.; Universidad EAFIT. Departamento de Geología; Ciencias del MarThe potential of the gulf of Urabá to hold a multi-purpose port motivated a sediment dynamics study to describe the seasonal sediment concentration patterns in this tropical region. Challenges addressed in this study include a complex three-dimensional flow pattern in a tropical estuary and the lack of in-situ measurements. To overcome such challenges, this study completed: (i) Measurements of suspended sediment concentrations during two climatic seasons and an extreme event (2010–2011); (ii) Definition of boundary conditions from global databases; (iii) Qualitative analysis of sediment concentrations from satellite imagery; and (iv) integration of the previously mentioned steps to build a process-based 3D sediment transport model. Seasonal patterns of suspended sediment concentrations were identified and corroborated by the agreement between model results, satellite imagery and field measurements. During the calm rainy season, the Atrato River turbid plume extends northward and dominates the sediment dynamics in the gulf. On the other hand, during the dry season and extreme events, bed transport is enhanced and the river's plume and the littoral drift shift southwards. © 2017 Elsevier LtdÍtem Two-dimensional transport analysis of transdermal drug absorption with a non-perfect sink boundary condition at the skin-capillary interface(ELSEVIER SCIENCE INC, 2013-07-01) Simon, Laurent; Ospina, Juan; Simon, Laurent; Ospina, Juan; Universidad EAFIT. Departamento de Ciencias; Lógica y ComputaciónA transient percutaneous drug absorption model was solved in two dimensions. Clearance of the topically-applied pharmaceutical occured at the skin-capillary boundary. Timolol penetration profiles in the dermal tissue were produced revealing concentration gradients in the directions normal and parallel to the skin surface. Ninety-eight percent of the steady-state flux was reached after 85. h or four time constants. The analytical solution procedure agreed with published results. As the clearance rate increased relative to diffusion, the delivery rate and amount of drug absorbed into the bloodstream increased while the time to reach the equilibrium flux decreased. Researchers can apply the closed-form expressions to simulate the process, estimate key parameters and design devices that meet specific performance requirements. © 2013 Elsevier Inc.