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    Development of a linear diattenuation sensitive semi-autonomous and portable digital lensless holographic microscope
    (Universidad EAFIT, 2022) Lopera Acosta, Maria Josef; Trujillo Anaya, Carlos Alejandro
    This document presents the development of a linear diattenuation sensitive, semi-autonomous and portable digital lensless holographic microscope (DLHM). With the development of this project, we aim to improve the performance of this microscopy technique and to broaden the possibilities for a portable DLHM device. We believe our microscope can potentially be used in the diagnosis of diseases. In order to address this aim, the following aspects were investigated within the scope of this project. i) The design of specialized illumination sources for DLHM that are efficient, mechanically stable, and easy to align. ii) The implementation of a DLHM sensitive to the linear diattenuation response of samples. iii) The study of machine-learning based autofocusing methods to be applied to DLHM holograms. iv) The design of specialized software to acquire and reconstruct DLHM holograms and iiv) the design and manufacture of proper mechanical couplings that integrate the DLHM setup with the cellphone’s digital sensor. Five papers and five proceedings are the resultant products of this thesis project. They constitute part of the core of this thesis and are attached by the end of the document.