Examinando por Materia "Biophysics"

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    Cerebral Cortex Atlas of Emotional States Through EEG Processing
    (SPRINGER, 2019-10-14) Gómez A.; Quintero O.L.; Lopez-Celani N.; Villa L.F.; Universidad EAFIT. Escuela de Ciencias; Modelado Matemático
    This paper addresses the cerebral cortex maps construction from EEG signals getting an information simplification method for an emotional state phenomenon description. Bi-dimensional density distribution of main signal features are identified and a comparison to a previous approach is presented. Feature extraction scheme is performed via windowed EEG signals Stationary Wavelet Transform with the Daubechies Family (1–10); nine temporal and spectral descriptors are computed from the decomposed signal. Recursive feature selection method based on training a Random forest classifier using a one-vs-all scheme with the full features space, then a ranking procedure via gini importance, eliminating the bottom features and restarting the entire process over the new subset. Stopping criteria is the maximum accuracy. The main contribution is the analysis of the resulting subset features as a proxy for cerebral cortex maps looking for the cognitive processes understanding from surface signals. Identifying the common location of different emotional states in the central and frontal lobes, allowing to be strong parietal and temporal lobes differentiators for different emotions. © 2020, Springer Nature Switzerland AG.
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    An Entropy-Based Graph Construction Method for Representing and Clustering Biological Data
    (SPRINGER, 2019-10-01) Ariza-Jiménez L.; Pinel N.; Villa L.F.; Quintero O.L.; Universidad EAFIT. Departamento de Ciencias; Ciencias Biológicas y Bioprocesos (CIBIOP)
    Unsupervised learning methods are commonly used to perform the non-trivial task of uncovering structure in biological data. However, conventional approaches rely on methods that make assumptions about data distribution and reduce the dimensionality of the input data. Here we propose the incorporation of entropy related measures into the process of constructing graph-based representations for biological datasets in order to uncover their inner structure. Experimental results demonstrated the potential of the proposed entropy-based graph data representation to cope with biological applications related to unsupervised learning problems, such as metagenomic binning and neuronal spike sorting, in which it is necessary to organize data into unknown and meaningful groups. © 2020, Springer Nature Switzerland AG.
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    An Entropy-Based Graph Construction Method for Representing and Clustering Biological Data
    (SPRINGER, 2019-10-01) Ariza-Jiménez L.; Pinel N.; Villa L.F.; Quintero O.L.; Universidad EAFIT. Departamento de Ciencias; Biodiversidad, Evolución y Conservación
    Unsupervised learning methods are commonly used to perform the non-trivial task of uncovering structure in biological data. However, conventional approaches rely on methods that make assumptions about data distribution and reduce the dimensionality of the input data. Here we propose the incorporation of entropy related measures into the process of constructing graph-based representations for biological datasets in order to uncover their inner structure. Experimental results demonstrated the potential of the proposed entropy-based graph data representation to cope with biological applications related to unsupervised learning problems, such as metagenomic binning and neuronal spike sorting, in which it is necessary to organize data into unknown and meaningful groups. © 2020, Springer Nature Switzerland AG.
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    Ítem
    An Entropy-Based Graph Construction Method for Representing and Clustering Biological Data
    (SPRINGER, 2019-10-01) Ariza-Jiménez L.; Pinel N.; Villa L.F.; Quintero O.L.; Universidad EAFIT. Escuela de Ciencias; Modelado Matemático
    Unsupervised learning methods are commonly used to perform the non-trivial task of uncovering structure in biological data. However, conventional approaches rely on methods that make assumptions about data distribution and reduce the dimensionality of the input data. Here we propose the incorporation of entropy related measures into the process of constructing graph-based representations for biological datasets in order to uncover their inner structure. Experimental results demonstrated the potential of the proposed entropy-based graph data representation to cope with biological applications related to unsupervised learning problems, such as metagenomic binning and neuronal spike sorting, in which it is necessary to organize data into unknown and meaningful groups. © 2020, Springer Nature Switzerland AG.
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    Standardized Approaches for Assessing Metagenomic Contig Binning Performance from Barnes-Hut t-Stochastic Neighbor Embeddings
    (SPRINGER, 2020-01-01) Ceballos J.; Ariza-Jiménez L.; Pinel N.; Ceballos J.; Ariza-Jiménez L.; Pinel N.; Universidad EAFIT. Departamento de Ciencias; Ciencias Biológicas y Bioprocesos (CIBIOP)
    The performance of unsupervised methods for metagenomic binning is often assessed using simulated microbial communities. The lack of well-characterized evaluation protocols and approaches to community construction cognizant of biological realities impedes the rigorous assessment and standardization of the binning process. This work attempted to standardize performance evaluation using benchmark communities constructed according to the genome similarity metric Average Amino Acid identity. This approach allowed us to extend and deepen our previous research on the unsupervised binning of metagenomic sequence fragments based on low-dimensional embeddings of pentamer frequency profiles. Experimental results evidenced our method’s potential for the binning of metagenomic contigs to become an alternative to state-of-the-art methods such as MetaCluster 3.0. © 2020, Springer Nature Switzerland AG.
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    Standardized Approaches for Assessing Metagenomic Contig Binning Performance from Barnes-Hut t-Stochastic Neighbor Embeddings
    (SPRINGER, 2020-01-01) Ceballos J.; Ariza-Jiménez L.; Pinel N.; Ceballos J.; Ariza-Jiménez L.; Pinel N.; Universidad EAFIT. Departamento de Ciencias; Modelado Matemático
    The performance of unsupervised methods for metagenomic binning is often assessed using simulated microbial communities. The lack of well-characterized evaluation protocols and approaches to community construction cognizant of biological realities impedes the rigorous assessment and standardization of the binning process. This work attempted to standardize performance evaluation using benchmark communities constructed according to the genome similarity metric Average Amino Acid identity. This approach allowed us to extend and deepen our previous research on the unsupervised binning of metagenomic sequence fragments based on low-dimensional embeddings of pentamer frequency profiles. Experimental results evidenced our method’s potential for the binning of metagenomic contigs to become an alternative to state-of-the-art methods such as MetaCluster 3.0. © 2020, Springer Nature Switzerland AG.
  • No hay miniatura disponible
    Ítem
    Standardized Approaches for Assessing Metagenomic Contig Binning Performance from Barnes-Hut t-Stochastic Neighbor Embeddings
    (SPRINGER, 2020-01-01) Ceballos J.; Ariza-Jiménez L.; Pinel N.; Ceballos J.; Ariza-Jiménez L.; Pinel N.; Universidad EAFIT. Departamento de Ciencias; Bioiversidad, Evolución y Conservación
    The performance of unsupervised methods for metagenomic binning is often assessed using simulated microbial communities. The lack of well-characterized evaluation protocols and approaches to community construction cognizant of biological realities impedes the rigorous assessment and standardization of the binning process. This work attempted to standardize performance evaluation using benchmark communities constructed according to the genome similarity metric Average Amino Acid identity. This approach allowed us to extend and deepen our previous research on the unsupervised binning of metagenomic sequence fragments based on low-dimensional embeddings of pentamer frequency profiles. Experimental results evidenced our method’s potential for the binning of metagenomic contigs to become an alternative to state-of-the-art methods such as MetaCluster 3.0. © 2020, Springer Nature Switzerland AG.