Examinando por Materia "Antibacterial activity"

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    Lipopeptides from Bacillus sp. EA-CB0959: Active metabolites responsible for in vitro and in vivo control of Ralstonia solanacearum
    (Academic Press Inc., 2018-07-31) Villegas Escobar, Valeska; González-Jaramillo LM; Ramirez, Maria; MONCADA, RUTH NATALIA; Sierra Zapata, Laura; Orduz, Sergio; Romero, Magally; Universidad EAFIT. Departamento de Ciencias; Ciencias Biológicas y Bioprocesos (CIBIOP)
    Broadening the spectrum of action of microbial bioactive compounds is a priority nowadays. From a collection of 1493 aerobic endospore forming bacteria, 3.1% (47) inhibited Serratia marcescens and were highly active against R. solanacearum. Thirty-six of these strains were identified as part of the ‘Operational Group B. amyloliquefaciens’ denoting the potential of strains from these species to produce antibacterial substances. Specifically, the strain Bacillus sp. EA-CB0959 was selected for further trials. Three families of lipopeptides: surfactins, iturins and fengycins were found as the active compounds produced by this strain. The highest bioactivity, produced by fengycins, had a minimal inhibitory concentration of 32 µg/mL. Treating greenhouse banana plants with a mixed fraction of lipopeptides reduced by 35% the incidence of Moko disease caused by R. solanacearum. Here we provide first time evidence of in vitro antibacterial activity of purified fengycins and in vivo activity of mixed lipopetides against Moko disease in banana plants. © 2018 Elsevier Inc.